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Physiome publishes reproducible and reusable mathematical models of physiological processes where the experimental details and model validation have been published or accepted for publication in a recognised 'primary' peer-reviewed journal. Physiome curators will help authors ensure that models and simulation experiments are made available using appropriate community standards prior to acceptance for publication in Physiome. When aspects of a computational modelling study are not able to be encoded in standard formats, Physiome curators will help authors ensure their work is as open, reproducible, and reusable as possible.

Physiome editors will help as much as is currently possible with model curation and annotation to ensure that the modeling results claimed in the primary paper are consistent with the published model. Physiome is open access with a low Author Processing Charge. Models can be displayed and, in some cases, run directly from the journal website with freely available open source software.

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Latest articles

Computational Modeling of Coupled Energetics and Mechanics in the Rat Ventricular Myocardium

Marzban, B. , Lopez, R. , Beard, D. A.

Model of skeletal muscle cramp and its reversal

Tasaki, K. , Noble, P. J. ORCID logo , Garny, A. ORCID logo , Shorten, P. R. ORCID logo , Afshar, N. ORCID logo , Noble, D. ORCID logo

Incorporation of sarcolemmal calcium transporters into the Shorten et al. (2007) model of skeletal muscle: equations, coding, and stability

Noble, P. J. ORCID logo , Garny, A. ORCID logo , Shorten, P. R. ORCID logo , Tasaki, K. , Afshar, N. ORCID logo , Noble, D. ORCID logo

The Boron & De Weer Model of Intracellular pH Regulation

Occhipinti, R. ORCID logo , Safaei, S. ORCID logo , Hunter, P. J. ORCID logo , Boron, W. F. ORCID logo

The cardiac Na+/K+ ATPase: An updated, thermodynamically consistent model

Pan, M. ORCID logo , Gawthrop, P. J. ORCID logo , Cursons, J. ORCID logo , Tran, K. ORCID logo , Crampin, E. J.

Bond Graph Model of Cerebral Circulation: Toward Clinically Feasible Systemic Blood Flow Simulations

Su, S. ORCID logo , Blanco, P. J. ORCID logo , Müller, L. O. ORCID logo , Hunter, P. J. ORCID logo , Safaei, S. ORCID logo