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Frequently Asked Questions

What is the difference between a primary publication and a Physiome publication?

The primary publication is an experimental or modelling paper describing the model, and has been accepted to a peer-reviewed journal in the field of physiological modelling. The primary publication demonstrates that the model presented in the Physiome article has been scientifically reviewed. In addition, it will typically include relevant biological background, and explain why the model was developed.

Physiome articles focus on reproducibility and reuse, but do not deal with the validation nor scientific relevance of the models: these are reviewed in the Primary Paper.

My code is already in my primary publication. Why do I need a Physiome publication?

A Physiome article enables you to fully describe your model implementation and its use to reproduce the findings of your primary publication. Also, any modifications made to the code since the publication of the primary publication can be finalised in order to meet reproducibility and reusability standards.

Does the primary publication need to be published before submitting the corresponding Physiome publication?

No: for original submissions, authors are encouraged to prepare their Physiome submission(s) in parallel to the primary publication. Submissions will be curated and evaluated, but not published until the primary publication is accepted and has been allocated a DOI.

In my submission, do I have to include code for every figure in the primary publication?

No. The Physiome article should, however, clearly describe which results from the primary publication can be reproduced by the implementation.

My code is in a specific deprecated language - must I translate it?

Code language does not have to be a standard markup language - as long as we can run it our computers and reproduce the expected results. Provide exact instructions on how to install or access the tools required to execute the files included in your submission.

What is a standard format?

A markup languages such as CellML, SBML, and NeuroML, designed to encode a model in unambiguous form. The markup language SED-ML is designed to specify the simulation protocol for running the model with specified inputs and outputs. The use of these standard formats improves the reusability of your model implementation.

See the Computational Modelling in Biology Network (COMBINE) for further information and guidance on the use of standards for modelling in biology.

What is OMEX?

Physiome articles include a COMBINE archive containing all files required for implementation of the model and reproduction of the simulation results presented. It can be opened by any type of ZIP reader.

The Open Modelling Exchange format, OMEX, is the technical specification defining the format of the COMBINE archive.

I can't find my Physiome publication on pubmed/worldcat?

Each article has a DOI unique to it - it is not the same as the primary publication's. You will see your Physiome publication on international databases soon.

What is the impact factor for Physiome?

We are a new journal! We are working on appearing on various international databases.

Where are the physical Physiome issues?

We are an online only journal, publishing as soon as submissions are curated and accepted. Given the nature of the submissions, which are heavy on computer code, there are no physical copies of the journal.

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