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Original Article

Published: 2021-10-27
Last edited: 2021-10-27




Mathematical model of excitation-contraction in a uterine smooth muscle cell

Ai, W. ORCID logo , Freifeld, L. ORCID logo , Nickerson, D. P. ORCID logo

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To cite this Physiome article, cite the whole collection at the DOI: 10.36903/physiome.16828756, and the Primary Publication at the DOI: https://doi.org/10.1152/ajpcell.00478.2006.

All Physiome articles are published as a collection containing the manuscript as a PDF file and the model implementation as an OMEX file.


Primary Publication: Mathematical model of excitation-contraction in a uterine smooth muscle cell. 2007, L. Bursztyn, O. Eytan, A.J. Jaffa, D. Elad

Abstract: The Bursztyn et al. (2007) paper proposes a mathematical model of excitation-contraction in a myometrial smooth muscle cell (SMC). The model incorporates processes of intracellular Ca^2+ concentration control, myosin light chain (MLC) phosphorylation and stress production. We create a modularized CellML implementation of the model, which is able to simulate these processes against the original data.


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